With TGA Approval AlphaWave® is now the only source of L-Theanine approved for supplement use in Australia

AlphaWave® L-Theanine is widely used in the US where it is one of the most popular ingredients for stress-relief in both supplements and beverages. However, no source of L-Theanine has been permitted for use in Australia until AlphaWave® received approval from the Australian Therapeutic Goods Administration (TGA) for inclusion as an ingredient in listed medicines in Australia. This approval was received after 18 months of work by Ethical Naturals Inc. (ENI).

Cal Bewicke, CEO of ENI says: 'The application process through TGA is detailed and rigorous. It examines in-depth the manufacturing system, the analytical methods used and clinical data. This TGA approval adds to AlphaWave's® record of quality and safety confirmed though our clinical trials and GRAS affirmation.'

To read the full article click here.

ENI’s Cal Bewicke on botanical supply chain quality: ‘We consider ourselves gatekeepers’

Cal Bewicke was interviewed by Stephen Daniels at SupplySide West and they discussed current pressures on the botanical supply chain, the benefits of real US testing on materials, and the effects of climate change on high value botanical ingredients.

To read the full article click here.

ENI PhytoReport on Ginkgo Biloba Adulteration and Prevention

PhytoReport #4

Ginkgo Adulteration & Identification


Ginkgo biloba is the oldest living tree species on earth, dating back to the Paleozoic period, over 225 million years ago. The medicinal use of ginkgo leaf is first mentioned in Chinese medicine in the Ming dynasty, in 1436 [1].

In the present day, standardized Ginkgo biloba extract (GBE) has been one of the most popular and respected herbal remedies on both sides of the Atlantic for over 25 years. Ginkgo is also one of the most widely tested phytomedicines, and has been the subject of over 120 clinical studies, for cerebral insufficiency, dementia, and peripheral vascular disease.

To read the full article click here.

[1] 2012 Ethical Naturals Inc.

ABC Ginkgo Adulteration Report

Adulteration of Ginkgo biloba Leaf Extract

By Stefan Gafner, PhD*American Botanical Council, 6200 Manor Road,Austin, TX 78723*Corresponding author: email

Keywords: adulterant, adulteration, Ginkgo biloba,ginkgo leaf extract, Japanese pagoda tree, Japanesesophora, kaempferol, quercetin, rutin, Sophora japonica,Styphnolobium japonicum

Goal: The goal of this bulletin is to provide timely informationand/or updates on issues of adulteration of ginkgo(Ginkgo biloba) leaf and ginkgo leaf extracts to the internationalherbal industry and extended natural productscommunity in general. It is intended to give a brief overviewon the occurrence of adulteration, known adulterantsand analytical means to detect them, the market situation,and consequences for the consumer and the industry.

To read the full article click here.

[1] 2018 ABC.

NBJ Article by ENI CEO

Retail sales for botanical extract products continue to grow at 7-10 percent each year. This should be good news for consumers. In addition to the thousands of published studies that support the benefits of high grade extracts, as one herbalist said to me, “One of the things that I like about herbal supplements is that they have a focused ability to kickstart real change.” We’re talking here about the benefits of mainstream herbal extracts such as ginkgo, milk thistle, bilberry, turmeric and the others that form the mainline of herbal usage today.

Where does the supply of these products really stand? On one hand, there’s the genuine science supporting their benefits; on the other, reliable reports from ABC, AHP, and industry sources confirm the widespread use of adulterated materials, designed to reduce costs but consequently reduce beneficial outcomes.

To read the full article click here

[1] 2018 NBJ Dark Issue.



ENI Releases new Mushrooms-Plus product line

Sales of mushroom supplements have increased from 25% - 60% each year over the last three years [1]. To make a wider selection of premium mushroom supplements available to their customers, ENI has released their new MUSHROOMS-PLUS™ product line. These products contain organic mushroom extracts, with key ingredients that add to their consumer appeal and effectiveness. All the extracts are supplied by Nammex, and are standardized for Beta-D-Glucans levels.

Key products in the line are ReiCalm™, that combines Red Reishi extract with ENI’s AlphaWave® L-Theanine, and Ergothioneine-Plus, with Ergothioneine and Shitake mushroom extract.

For more information please go to MUSHROOMS-PLUS™ and ReiCalm™

[1] 2022 NBJ Herbs and Botanicals Report.

New clinical study with AlphaWave® L- Theanine confirms stress reduction in healthy adults

A new triple blind, placebo controlled clinical study, published in Neurology and Therapy finds that AlphaWave® increases frontal alpha power, an indication of relaxation without drowsiness, in addition to other objective markers of reduced stress and tension. This is the second study to confirm the relaxation benefits of AlphaWave® L-Theanine.

To read the full article click here
To access the full study click here

Worldwide shipping delays: where we stand at ENI

Date: 08 September, 2021


Almost every company in our industry has been impacted in some way by the current situation of worldwide shipping delays.

At Ethical Naturals (ENI) we’ve been preparing for this since Covid began in early 2020: working with our key manufacturers to build inventory and assure ongoing supply to our regular customers. In a recent interview for NutraIngredients, Cal Bewicke, ENI CEO, talked about our inventory position today:

‘As soon as Covid began, we progressively built more inventory, planning six, nine months ahead. That’s worked well for us, and we’ve been shipping out pretty much on time throughout this period.

We always carry substantial inventory; now it’s even larger. A number of companies rely on our proprietary ingredients like AlphaWave® L-Theanine, GreenGrown® Glucosamine, and the core botanical extracts that we supply. We won’t let those companies down.’

In answer to the question: ‘When do you anticipate it will return to normal?’ Cal stated:

‘Someday I expect we’ll return to a ‘new normal’, but I can’t say when that will be. The positive that’s come out of this situation is that many of us have come to see again the value of strong, dependable and well-invested supply chains at every level. That’s the way we move forward, by supporting each other in the quality investments of time and resources that we make into our industry. This goes for every step in the supply chain, from the field to the finished products.’


At ENI, we work to support your work.
The Team at Ethical Naturals

Links to two articles of interest:
"Port snarl in China shows shipping crisis from far over"
"A record-breaking 44 container ships are stuck off the coast of California".

Polyphenol-C™: a new premium vitamin-C provides wide-spectrum berry polyphenols for enhanced immune support

It’s been known for centuries that eating fruits prevented scurvy, but it wasn’t until 1930 Albert Szent-Gyorzi was awarded the Nobel Prize for discovering the identity of the vitamin-C molecule. The name given to it, ‘ascorbic acid’ literally means ‘anti-scurvy’.

To read the full article click here.

VinCare Clinical Study: Whole Grape Extract Supports Healthy Cholesterol and Cardiovascular Health

Grape extracts growing popularity

Grape extracts of all kinds: skin, seed and whole grape are reaching a new level of popularity with supplement buying consumers. This may be because we’re dealing with the new lifestyle challenges of today, when the extract benefits that support cardiovascular health and anti-oxidant activity mean even more to us than they did a year ago

To read the full article click here.

Cranberry’s unique A-Type PAC’s show significant UTH benefits through anti-adhesion acitvity (AAA)

Cranberry: the journey through nature and science

Cranberries, the beautiful red fruits of Vaccinium macrocarpon ​have been valued for many centuries for both their food and medicinal qualities. Indigenous to N.America, cranberries were widely used by Native Americans. They quickly became popular with settlers from Europe, and in 1672, in one of the earliest records of medicinal use, John Josselyn described Cranberries as being an excellent protection against scurvy [1]. By 1789 the fruit was so in demand that the New Jersey legislature restricted the harvesting of berries.

To read the full article click here.

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Ethical Naturals Inc., is certified to comply with NSF GMP Registration Program Requirements of NSF/ANSI 173, Section 8 which includes FSMA and cGMP (21 CFR 111), (21 CFR 117).

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